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. 2013 Mar 8;8(3):e58806. doi: 10.1371/journal.pone.0058806

Table 2. Genes with significant expression levels in serum-starved nucleus pulposus cells Only genes whose expression was significantly (P<0.05) up- or down-regulated at least 1.5 fold are shown.

GeneSymbol Description qRT-PCR Array
Fold change P value Fold change
Abl1 C-abl oncogene 1, receptor tyrosine kinase 1.78 0.033 1.28
Atm Ataxia telangiectasia mutated homolog (human) 1.86 0.015 1.43
Brca1 Breast cancer 1 1.57 0.020 1.69
Ccnd1 Cyclin D1 −1.51 0.024 −1.59
Cdc25a Cell division cycle 25 homolog A (S. pombe) 1.68 0.016 1.31
Gadd45a Growth arrest and DNA-damage-inducible, alpha 1.82 0.038 1.58
Hus1 HUS1 checkpoint homolog (S. pombe) 1.74 0.042 1.46
Bcl2 B-cell CLL/lymphoma 2 1.89 0.003 1.82
Rad21 RAD21 homolog (S. pombe) 1.62 0.003 1.49
Msh2 MutS homolog 2 (E. coli) 1.63 0.003 1.23
Notch2 Notch homolog 2 (Drosophila) 1.56 0.006 1.38
Ppm1d Protein phosphatase 1D magnesium-dependent, delta isoform 1.74 0.039 1.39
Rad9 RAD9 homolog (S. pombe) 1.64 0.013 1.37
Stag1 Stromal antigen 1 1.52 0.044 1.52
Terf1 Telomeric repeat binding factor (NIMA-interacting) 1 1.56 0.007 1.24
Tfdp2 Transcription factor Dp-2 (E2F dimerization partner 2) 1.78 0.020 1.39
Tp53 Tumor suppressor protein p53 2.07 0.010 1.403