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. 2013 Mar 8;8(3):e59026. doi: 10.1371/journal.pone.0059026

Figure 5. Effects of various inhibitors on Txnip suppression in response to LPS.

Figure 5

(A and B) RAW264.7 cells were treated with Vehicle (dimethyl sulfoxide in (A) or diethyl ether in (B)), 10 µM compound C (Comp. C), or 50 nM okadaic acid for 1 h, followed by stimulation with 100 ng/ml LPS for 90 min. (C) RAW264.7 cells were treated with 0.5 mM iodoacetate or sodium acetate for 1 h, followed by treatment with 100 ng/ml LPS, 5 mM sodium azide, or 5 µM rotenone for 90 min. Txnip mRNA copy numbers normalized to that of β-actin are shown. Data shown are mean ± S.E. of triplicate samples of a representative of at least three independent experiments.