Table 1. Comparison of the best performance achieved by iScore on three datasets.
Data set | Top N | Specificity | Sensitivity |
Domain-domain interfaces | 23 | 83.60% | 82.00% |
Homodimer interfaces | 24 | 82.67% | 82.67% |
Heterodimer interfaces | 28 | 78.87% | 84.67% |
The best performance was defined by selecting the top N scored structures to reach the highest possible specificity and sensitivity at the same time.