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. 2013 Mar 8;8(3):e57720. doi: 10.1371/journal.pone.0057720

Table 1. Characteristics of the prospective studies included in the meta-analysis of published studies on magnesium intake and the risk of CVD events.

Source Location/Follow-up, y Study Population (n) Sex/Age, y Recruitment Time Outcome(s) Outcomes Assessment Magnesium intake Assessment
Ascherio (1998) United States, 8 43,738 Male, 40–75 1986 Stroke Ascertained by self-report; subclassified accordingto the criteria of the National Survey of Stroke. Validated FFQ
Liao (1998) United States, 7 13,922 Female/Male, 45–64 1987–1989 CHD Ascertained by self-report and medical records, deathcertificates; reviewed by members of the ARIC Morbidityand Mortality Classification Committee FFQ
Iso (1999) United States, 14 85,764 Female, 34–59 1976 Stroke Ascertained by self-report and medical records;confirmed according to the criteria of theNational Survey of Stroke. Validated FFQ
Abbott (2003) United States, 30 7172 Male, 45–68 1965–1968 CHD Confirmation by the Honolulu Heart ProgramMorbidity and Mortality Review Committee. 24-hour dietary recall
Al-Delaimy (2004) United States, 12 39,633 Male, 40–75 1986 CHD Ascertained by self-report and medical records. Validated FFQ
Song (2005) United States, 10 39,876 Female, 39–89 1991 CVD Confirmed through medical records, autopsy reports,and death certificates. Validated FFQ
Larsson (2008) Finnish,13.6 26,556 Male, 50–69 1985–1988 Stroke Identified by National Hospital Discharge Register andthe National Register of Causes of Death and classifiedaccording to ICD-8,9,10 (ICD-8 codes 430–434,436; ICD-9codes 430, 431, 433, 434, 436; ICD-10 codes I60, I61, I63,and I64) Validated FFQ
Weng (2008) China, 10.6 1772 Female/Male, ≥40 1990–1993 Stroke Ascertained by self-reported; classified according toICD-9-CM (codes 430 to 438) FFQ
Ohira (2009) United States, 15 14,221 Female/Male, 45–64 1987–1989 Stroke Ascertained by self-report, local hospitals, state vitalstatistics offices; and classified according to ICD-9(codes 430–438) FFQ
Kaluza (2010) Swedish, 10 23,366 Male, 45–79 1997–1998 CVD death Review of Swedish Death and Population Registersand classified according to ICD-10 (codes I00–I79) Validated FFQ
Chiuve (2011) United States, 10 88,375 Female, 30–55 1976 CVD death Documented by medical records FFQ
Larsson (2011) Swedish,10.4 34,670 Female, 49–83 1987–1990 Stroke Ascertained by Swedish Hospital Discharge Registry andidentified according to ICD-10 (codes I60, I61, I63, I64) Validated FFQ
Zhang (2012) Japan, 14.7 58,615 Female/Male, 40–79 1988–1990 CVD death A systematic review of death certificates; and classifiedaccording to ICD-9 (codes 390–459) and ICD-10 (codes101–199) Validated FFQ

CHD = coronary heart disease; CVD = cardiovascular disease; FFQ = food frequency questionnaire; ICD = International Classification of Diseases.