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Metformin augments hepatic ER stress after burn. ER stress markers were assessed at the mRNA level. Chop is a downstream target of PERK, whereas Bip, Dnajb9 and Pdia3 are activated by the spliced form of Xbp-1. Both 24-h (A) and 48-h (B) postburn time points are shown. *p < 0.05, **p < 0.01 versus sham.
