. 2012 Jan 12;35(2):487–500. doi: 10.1007/s11357-011-9373-7

Table 3.

Danish case–control study; gene-based test of PCCAs

Gene	No. of SNPs genotyped	Single-SNP-based test (PCCA < 0.05)			Gene-set-based test
Gene	No. of SNPs genotyped	SNP	PCCA	OR	P-set
CETP	20	rs1800777	0.020	1.517	1 × 10⁻⁵
		rs289714	0.019	1.233
		rs4784744	0.027	0.856
		rs5883	0.022	1.385
		rs9923854	4.42 × 10⁻¹⁰	1.948
		rs9930761	0.004	1.460
APOE	3	rs405509	0.025	0.859	0.0016
APOE	3	rs769449	0.0002	0.700	0.0016
HSPA14	6	rs12770830	0.011	1.346	0.0019
		rs17268499	0.004	1.292
		rs7905174	0.005	1.236
		rs9787671	0.001	1.343
SIRT6	3	rs107251	0.001	1.348	0.0043

PCCA allelic case–control comparison P value, OR odds ratio, P-set set/gene-based test