Table 1.

Univariate regression analysis to estimate the relationship between TBEV-specific CD4⁺T cell populations, age and plasma TBEV-neutralizing Ab titres and TBEV-IgG

Predictor	TBEV-neutralizing Ab		TBEV-IgG (ELISA)
	Coefficient	p value	Coefficient	p value
Age	−0.777	<0.001	−0.593	<0.001
IL-2	0.638	0.005	0.719	<0.001
TNF	0.416	0.014	0.451	0.014
IFN-γ	0.261	0.234	0.228	0.235
CD154	0.379	0.059	0.362	0.058

Standardized coefficients and p-value of log TBEV-specific CD4⁺T cells expressing IL-2, TNF, IFN-γ or CD154 on log TBEV-neutralizing Ab titres and log TBEV-IgG (VIE U/ml) after TBE primary vaccination