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. Author manuscript; available in PMC: 2013 Mar 10.
Published in final edited form as: Int Rev Neurobiol. 2010;91:289–320. doi: 10.1016/S0074-7742(10)91009-X

FIG. 3.

FIG. 3

Up-states in PFC slice cultures are inhibited by ethanol. Panel A shows arrangement of prefrontal cortex (PFC), hippocampus (HP), and ventral tegmental area (VTA) in brain slice co-culture. Picture shows dopamine neurons stained for tyrosine hydroxylase (TH). Panel B shows example of up-states recorded from a deep-layer PFC pyramidal neuron. Ethanol reversibly inhibits up-state activity at a concentration of 25 mM (panel D) but not 10 mM (panel C). Taken from Tu et al. (2007).