Table 6.
Study | Study population | Characteristics | N | Design | Main findings * |
---|---|---|---|---|---|
Janousek et al. 2001 [84] |
Congenital Heart
disease |
Children with acute post-operative HF with conduction delay |
20 | Prospective study |
Beneficial effects. Improvement in hemodynamics (systolic blood pressure) |
Dubin et al. 2003 [85] |
Congenital Heart
disease |
Chronic RV dysfunction RBBB TOF, aortic stenosis after Ross procedure |
7 | Prospective Multipacing sites, conductance catheter |
Beneficial effect. Atrioventricular augments RV and systemic performance (↑CI by 17±8%,↑ in RV dP/dt ) |
Janousek et al. 2004 [86] |
Congenital Heart
Disease |
D-TGA (atrial baffle) L-TGA | 8 | Prospective |
Beneficial effect. ↑ RVEF by 9.6%, ↓ RVMPI by 7.7%. |
Dubin et al. 2005 [87] |
Congenital Heart
Disease and Pediatric |
CHD and dilated CMP and congenital AV block |
103 | Multicenter Study (22 centers) |
Beneficial effects in all 3 groups. Average ↑ in EF 11.9% to 16.1%. Responders had lower baseline EF. |
Unless otherwise specified, the results refer to statistically significant findings (p<0.05). The changes reported refer to relative changes in mean effect size or when indicated by ‡ changes in absolute effect size. Abbreviations as in previous tables. EF indicates ejection fraction, RVMPI indicates RV myocardial performance index