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Study design. All patients were given H. pylori eradication therapy (omeprazole 20 mg b.i.d., clarithromycin 400 mg b.i.d., and amoxicillin 750 mg b.i.d.) for 1 week, and eradication status was validated 3 months later. The QOLRAD-J questionnaire survey, the CDQ questionnaire surveys, and serum pepsinogen test were performed before, and at 3 months and 1 year after eradication therapy.
