Table 2.
Tumor # | Cytogenetics | BCR/TCR-based tumor type | Oncogene amplifications | Tumor suppressor deletions | Fragile site gene CNA | MLL rearrangement partners amplified |
---|---|---|---|---|---|---|
MPr14-111 | 40,XX | CLP-like | Ebf1, Cdkn2a | Lpp | ||
MPr14-143 | 40,XX | Precursor-B | Eg5 | |||
MPr14-185 | 43,XY,+14,+15,+17 | Precursor-B | Eg5, Tbx2 | Cdkn2a | Mllt10 | |
MPr14-189 | 40,XY,del(18qD1→qter), del(19qter→qB) | Precursor-B | Tbx2 | Mllt10, Ell, Mllt3 | ||
MPr14-217 | 40,XY | Precursor-B | Notch1, Tcf3, Tbx2 | Ebf1 | Grid2 | |
MPr14-218 | 41,XY,+1 | Precursor-B | Ebf1 | Wwox | Ell | |
MPr14-148 | 40,XX | Precursor-T | Eg5 | |||
MPr14-258 | 40,XX | Precursor-T | Eg5 | Ell, Eps15, Lpp | ||
MPr14-147 | 42,XX,+14,+15 | Mixed | Eg5 | Pax5 | Grid2 | Mllt10 |
MPr14-197 | 40,XY | Mixed | Mycl1, Eg5, Tbx2 | Cdkn2a, Fhit | Fhit | Mllt10, Lpp |
MPr14-228 | 41,XY,+2 | Mixed | Lmo1 | Ikzf1 | Wwox | Mllt10, Ell, Lpp |
MPr14-196 | 40,XY | Unclassified | Lmo1, Eg5 | Cdkn2a |