Table 2. HDACs Isoform Selectivity of 17a and SAHA^a.

	class I			class IIb	class IIa
compd	HDAC1	HDAC2	HDAC3	HDAC6	cell lysate
17a	0.39 ± 0.12	1.42 ± 0.06	0.28 ± 0.13	0.94 ± 0.14	NAb
SAHA	0.076 ± 0.011	0.256 ± 0.003	0.028 ± 0.011	0.118 ± 0.012	NAb

^aAssays were performed in replicate (n ≥ 2). IC₅₀ (μM) values are shown as means ± SDs.

^bNA, not active at 10 μM.