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Lymphocyte infiltration of tumors is similar in the four treatment groups. CT-26HER2/neu tumors from mice treated with PBS, IL-12, 4D5, or a combination of both agents were stained for (A) CD4+ lymphocytes and (B) CD8+ lymphocytes. Representative tumor sections from each treatment group are shown with arrows depicting Novared positive CD4 and CD8 stained T cells. Original magnification ×40 (all fields).
