Table 2. Hazard ratios over different time points.
|
Percentage (n) with cancer after zoster |
|||||
|---|---|---|---|---|---|
| Within 90 days of zoster | Within 180 days of zoster | Within 1 year of zoster | Within 3 years of zoster | Within 5 years of zoster | |
|
All patients | |||||
| Zoster (n=13 428) | 0.3 (45) | 0.6 (84) | 1.2 (154) | 3.2 (424) | 4.9 (658) |
| No zoster (n=60 601) | 0.0 (10) | 0.1 (41) | 0.3 (162) | 1.2 (715) | 2.3 (1396) |
| HR (95% CI) |
20.5 (10.4, 40.8) |
9.4 (6.5, 13.7) |
4.4 (3.6, 5.5) |
2.9 (2.5, 3.3) |
2.4 (2.2, 2.7) |
|
All males | |||||
| Zoster (n=5625) | 0.4 (21) | 0.8 (43) | 1.4 (77) | 3.6 (200) | 5.6 (307) |
| No zoster (n=25 198) | 0.0 (5) | 0.1 (17) | 0.3 (74) | 1.3 (338) | 2.7 (689) |
| HR (95% CI) |
19.1 (7.2, 50.5) |
11.6 (6.6, 20.3) |
4.8 (3.5, 6.6) |
2.9 (2.4, 3.4) |
2.3 (2.0, 2.6) |
|
All females | |||||
| Zoster (n=7803) | 0.3 (24) | 0.5 (41) | 1.0 (77) | 2.9 (224) | 4.5 (351) |
| No zoster (n=35 403) | 0.0 (5) | 0.1 (24) | 0.3 (88) | 1.1 (377) | 2.0 (707) |
| HR (95% CI) |
22.0 (8.4, 57.7) |
7.9 (4.8, 13.1) |
4.1 (3.0, 5.6) |
2.9 (2.4, 3.4) |
2.5 (2.2, 2.9) |
|
Males >65 | |||||
| Zoster (n=2188) | 0.9 (19) | 1.5 (33) | 2.7 (58) | 6.5 (142) | 9.9 (216) |
| No zoster (n=10 090) | 0.0 (4) | 0.1 (14) | 0.6 (59) | 2.8 (284) | 5.6 (561) |
| HR (95% CI) |
22.2 (7.6, 65.3) |
11.2 (5.9, 20.8) |
4.8 (3.3, 6.8) |
2.5 (2.1, 3.1) |
2.1 (1.8, 2.4) |
|
Females >65 | |||||
| Zoster (n=3297) | 0.5(17) | 0.9 (29) | 1.6 (53) | 4.8 (158) | 6.9 (229) |
| No zoster (n=15 186) | 0.0 (4) | 0.1 (19) | 0.4 (65) | 1.8 (277) | 3.3 (499) |
| HR (95% CI) | 19.9 (6.7, 59.0) | 7.2 (4.0, 12.9) | 3.9 (2.7, 5.6) | 2.9 (2.3, 3.5) | 2.4 (2.1, 2.8) |
Abbreviations: CI=confidence interval; HR=hazard ratio.