Table 2. Baseline adenoma characteristics by dietary polyamine group (baseline cohort; n=222).
| Dietary polyamine quartiles 1–3 (n=166) | Dietary polyamine quartile 4 (n=56) | Pa | |
|---|---|---|---|
|
Location | |||
| Right sided (n=92) | 64 (38.6%) | 28 (50.0%) | 0.13 |
| Left sided (n=130) |
102 (61.5%) |
28 (50.0%) |
|
| Mean adenoma number |
2.63 (±2.32 s.d.) |
2.39 (±1.89 s.d.) |
0.86 |
|
Number of adenomas | |||
| 1 | 68 (41.0%) | 25 (44.6%) | 0.16 |
| 2 | 44 (26.5%) | 8 (14.3%) | |
| ⩾3 (multiple adenomas) | 51 (30.7%) | 23 (41.1%) | |
| Missing |
3 (1.8%) |
0 (0%) |
|
| Advanced adenoma histologyb |
26 (15.7%) |
13 (23.2%) |
0.20 |
| Large adenomas (⩾1 cm) |
44 (26.5%) |
24 (42.9%) |
0.022 |
| High-risk adenomasc | 86 (51.8%) | 39 (69.6%) | 0.020 |
a
Wilcoxon rank-sum test P-values are reported for the comparison of mean adenoma number; otherwise, P-values are reported using χ2-tests for independence. All statistical tests were two-sided.
b
Includes adenomas with villous or tubulovillous features, high-grade dysplasia and carcinoma in situ.
c
Includes adenomas >1 cm in size, multiple adenomas (three or more at baseline), or those with the following histological characteristics: villous or tubulovillous features, high-grade dysplasia and carcinoma in situ.