Table 2. The correlation between the serum miR-1246 expression and clinicopathological factors of ESCC.
| Characteristics | n | High miR-1246 expression | Low miR-1246 expression | P-value |
|---|---|---|---|---|
| Total (%) |
101 |
28 (27.7) |
73 (72.3) |
|
|
Sex | ||||
| Male (%) |
89 |
25 (28.1) |
64 (71.9) |
1 |
| Female (%) |
12 |
3 (25.0) |
9 (75.0) |
|
|
Age | ||||
| <65 (%) |
30 |
8 (26.7) |
22 (73.3) |
0.9290 |
| 65⩽ (%) |
71 |
20 (28.2) |
51 (71.8) |
|
|
Tumour depth | ||||
| T1–2 (%) |
48 |
6 (12.5) |
42 (87.5) |
0.0024 |
| T3–4 (%) |
53 |
22 (41.5) |
31 (58.5) |
|
|
Lymph node metastasis | ||||
| Negative (%) |
46 |
4 (8.7) |
42 (91.3) |
0.0002 |
| Positive (%) |
55 |
24 (43.6) |
31 (56.4) |
|
|
Distant metastasis | ||||
| Negative (%) |
85 |
18 (21.2) |
67 (78.8) |
0.0020 |
| Positive (%) |
16 |
10 (62.5) |
6 (37.5) |
|
|
Stage | ||||
| I–II (%) |
51 |
6 (11.8) |
45 (88.2) |
0.0007 |
| III–IV (%) |
50 |
22 (44.0) |
28 (56.0) |
|
|
Survival of patients | ||||
| Alive (%) |
81 |
16 (19.8) |
65 (80.2) |
0.0009 |
| Dead (%) |
20 |
12 (60.0) |
8 (40.0) |
|
|
Resectability of tumour | ||||
| Resectable (%) |
67 |
13 (19.4) |
54 (80.6) |
0.0087 |
| Non-resectable (%) | 34 | 15 (44.1) | 19 (55.9) | |
Abbreviation: ESCC=oesophageal squamous cell carcinoma. Bold numbers indicate the significance level was set at P<0.05.