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. 2012 Apr 5;23(4):786–800. doi: 10.1093/cercor/bhs072

Figure 8.

Figure 8.

Structural and functional (resting-state) human brain connectomes. (a–c) Structural connectomes in adolescent (n = 22), adult (n = 44), and elderly (n = 23) groups. Each structural connectome is obtained by the averaged structural connectivity between each pair of DICCCOLs in each age group. The color bar at the bottom of c encodes the number of streamline fibers (from 10 to 150). (d–f) Functional connectomes in the 3 age groups. Each functional connectome is obtained by the averaged functional connectivity between each pair of DICCCOLs in each age group. The color bar at the bottom of f encodes the average functional connectivity (from 0.45 to 0.8). (g–i) The percentages of functional connections in d–f that are coincident with direct and indirect (up to 4 path lengths) structural connections, for 3 age groups, respectively. The horizontal axis represents the threshold used to select the functional connection edges and the number of selected functional edges in the connectivity matrix, and the vertical axis is the ratio of structural connections that are coincident with functional connections. Path length 1 (red curve) means direct structural connection between 2 DICCCOLs, while path length 2 (green curve), 3 (blue curve), and 4 (pink curve) represent 2–4 structural connection edges between 2 DICOOOLs. In particular, the black dotted curves in g shows that around 80% of functional connections in d in the adolescent group have direct or indirect structural connections. We can see similar black dotted curves in h and i for the adult and elder groups. (j) Percentages of common structural connectome edges between 2 groups and across 3 groups. The horizontal axis stands for the thresholds used to select the structural connection edges and the numbers of selected edges in the connectivity matrix, and the vertical axis is the ratio of common structural edges between 2 or 3 structural connectivity matrices. (k) Percentages of common functional connectome edges between 2 groups and across 3 groups. The horizontal axis represents the thresholds used to select the functional connection edges and the numbers of totally selected edges in the functional connectivity matrix, and the vertical axis is the ratio of common functional edges between 2 or 3 functional connectivity matrices.