Schematic of volume controlled isolated supported ventricle (VCISV). A, coronary perfusion tube; AV, air vent; B, sealed box in which heart was placed for testing; BC, Bellofram cylinder; C, comparator; E, error signal; EDV, end diastolic volume; ESV, end systolic volume; HE, heat exchanger; LT, linear displacement transducer; LV, left ventricle; NP, negative pressure applied behind the diaphragm to reduce the compliance of the rolling diaphragm; PA, power amplifier; V, coronary venous return tube; VP, ventricular pressure measured by a miniature gage; VV, ventricular volume signal; W, hydraulic fluid (water) (136).