Figure 14.
pressure-controlled isolated supported ventricle (PCISV) model showing the effect that changes in resistance and compliance have on the left ventricular pressure, aortic pressure, and aortic flow measured from cat left ventricle. Distal resistance was increased from a control value of 28.5 g/(cm4s) to 61 and 137 g/(cm4s). Aortic compliance was decreased from a control value of 43 cm4s2/g to 14 and 3.6 cm4s2/g. Heart rate was maintained constant at 153 beats/min by pacing. Results from this model for aggregated data from six feline PCISV hearts exposed to a 208% increase in resistance and a 21% decrease in compliance are given in Table 3. Similar results were obtained for changes in the resistance and compliance parameters of PCISV hearts from dogs (33).