Table 2.
Baseline Characteristics by Presence or Absence of Motoric Cognitive Risk (MCR) syndrome status
| Variables | MCR (n = 52) | Not MCR (N = 715) | p value |
|---|---|---|---|
| Age | 79.9±5.9 | 79.7±5.4 | .711 |
| Sex (women), % | 60 | 61 | .846 |
| Education years | 13.7±3.6 | 14.0±3.4 | .399 |
| Mean follow-up, months | 27.9±20.5 | 43.4±27.4 | <.001 |
| Cognitive complaints, % | 100 | 39 | <.001 |
| Slow gait, % | 100 | 9 | <.001 |
| Race, % | |||
| White | 56 | 71 | .025 |
| Black | 44 | 25 | .002 |
| Medical illness index (range 0–10) | 1.9±1.2 | 1.2±1.0 | <.001 |
| Strokes, % | 15 | 9 | .135 |
| Coronary artery disease, % | 15 | 9 | .128 |
| Previous myocardial infarction, % | 8 | 5 | .352 |
| Congestive heart failure, % | 4 | 2 | .296 |
| Hypertension, % | 75 | 60 | .035 |
| Diabetes, % | 31 | 14 | .001 |
| Depression, % | 15 | 11 | .341 |
| Parkinson’s disease, % | 2 | 1 | .297 |
| Chronic obstructive pulmonary disease, % | 10 | 5 | .182 |
| Arthritis, % | 13 | 4 | .012 |
| Clinical gait abnormality, % | 85 | 34 | <.001 |
| Neurological gait abnormality, % | 31 | 9 | <.001 |
| Non-neurological gait abnormality, % | 29 | 12 | <.001 |
| CDR score ≥0.5, % | 60 | 26 | <.001 |
| Gait speed, cm/s | 59.5±13.1 | 96.9±21.8 | <.001 |
| Blessed test score (range 0–32) | 3.3±2.3 | 2.1±2.2 | .001 |
| Free recall (range 0–48) | 28.7±6.5 | 31.3±6.0 | .002 |
| Digit symbol substitution test | 33.7±14.4 | 42.8±13.9 | <.001 |
| Digit span total | 12.9±2.9 | 14.1±3.5 | .017 |
| Category fluency test | 31.3±8.1 | 37.5±8.9 | <.001 |
| Letter fluency test | 28.5±10.7 | 36.4±12.6 | <.001 |
| Trail making test B | 169.6±69.3 | 128.7±56.5 | <.001 |
| Geriatric depression scale (range 0–15) | 3.5±2.7 | 2.1±2.2 | <.001 |
Note: CDR = Clinical Dementia Rating scale.
Values are means ± SD unless otherwise noted.