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. Author manuscript; available in PMC: 2013 Apr 4.
Published in final edited form as: Sci Transl Med. 2012 Apr 4;4(128):128ra42. doi: 10.1126/scitranslmed.3003647

Table 2.

Public motifs that emerged among donors in this and previous reports of CMV-NLV-specific TCR repertoire.

Motif No. Public CDR3α motif Donors and previous reports in which public motif was found Prevalence among all responses in this study (%)
1 *nGNQF Y2, E3, E4, Trautmann, et al. (23), Day, et al. (25) 14.1
2 *nYGQNF Y1, E2, Trautmann, et al. (23), Day, et al. (25) 2.1
3 *nNNNDM Y2, E2, E4, Trautmann, et al. (23) 10.5
4 *nNFGNEKL E2, Trautmann, et al. (23) 2.1
5 *nTGANNL Y1, E2, Trautmann, et al. (23) 1.6
6 *nTGGGNKL Y1, E4 5.1
7 *nTSYDKV E2, Trautmann, et al. (23) 1.6

Public CDR3β motif

8 S*nTG*nGY Y2, E1, E2, E4, Weekes, et al. (21), Trautmann, et al. (23), Price, et al. (24), Day, et al. (25), Khan, et al. (22) 13.0
9 S*nTEA Y1, E2, E4, Weekes, et al. (21), Trautmann, et al. (23), Price, et al. (24), Day, et al. (25), Khan, et al. (22), Venturi, et al. (27) 11.7
10 *nTDTQ Y1, Trautmann, et al. (23), Price, et al. (24), Day, et al. (25) 4.3
11 *nRD*nG*YEQ E3, Day, et al. (25), Khan, et al. (22) 9.7
12 *nSYEQ Y1, E2, Weekes, et al. (21), Price, et al. (24), Khan, et al. (22) 1.5
13 *nTSGALYNEQ E3, Trautmann, et al. (23) 6.1

*n denotes a variable region of the public motif consisting of n amino acids, where n can range from 1 to 10. Percentages in this table are derived from all responses (N = 297 TCR sequences), regardless of whether TCRα and β co-expression data are available.