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. Author manuscript; available in PMC: 2013 Mar 11.
Published in final edited form as: DNA Repair (Amst). 2011 Oct 29;10(12):1282–1293. doi: 10.1016/j.dnarep.2011.10.008

Figure 6. Role of XRCC1 and AAG in human glioblastoma cells following exposure to NO.

Figure 6

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Base excision repair intermediates in human glioblastoma cells exposed to (A) 10% NO·, (B) 100% NO· for LN428WT and AAG over-expressing cells (AAGOE) and (C) 100% NO· for XRCC1 deficient (XRCC1-KD) cells and XRCC1 deficient, AAG over-expressing cells (AAGOE/XRCC1-KD). Asterisk indicates that the average difference for AAGOE/XRCC1-KD versus XRCC1-KD is significantly greater than zero (95% CI). Toxicity in human glioblastoma cells following exposure to (D) 10% NO·, (E) 100% NO· for LN428WT and AAG over-expressing cells (AAGOE) and (F) 100% NO· for XRCC1 deficient (XRCC1-KD) cells and XRCC1 deficient, AAG over-expressing cells (AAGOE/XRCC1-KD).