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. 2013 Mar 1;30(5):382–391. doi: 10.1089/neu.2012.2536

FIG. 3.

FIG. 3.

Lesion volume after single and sequential controlled cortical impact (CCI) and closed head injury (CHI). (A) Post-injury lesion size was greater in CCI versus sham CCI groups (p<0.0001) and was greater in CCI-CHI (53 g) and CHI (53 g)-CCI compared with CCI alone (p<0.05). Lesion size in CCI-CHI (53 g) did not differ from that of CHI (53g)-CCI (p=0.25). *p <0.0001 and **p<0.05 (B) Similar to results with CHI (53 g), lesion volume after injury was significantly greater in CCI-CHI (83 g) compared with CCI alone (p<0.001) but did not differ from that of CCI-CHI (53 g) (p=0.55). **p<0.001 vs. CCI and *p<0.0001 vs. sham CCI.