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. 2013 Mar 1;30(5):382–391. doi: 10.1089/neu.2012.2536

FIG. 4.

FIG. 4.

Motor performance after single and sequential controlled cortical impact (CCI) and closed head injury (CHI). (A) No difference in wire-grip test performance was observed between sham-injured CCI and CHI mice. (B) Compared with sham-injured mice and to CHI (53g) alone, CCI, CCI-CHI (53 g), and CHI (53 g)-CCI produced deficits in the wire-grip test (p<0.005 for group for each comparison to sham or CHI [53 g]). Neither CCI-CHI (53 g) nor CHI (53 g)-CCI, however, had motor deficits greater than CCI alone, and CCI-CHI (53 g) performed similarly to CHI (53 g)-CCI. (C) Motor deficits after CCI-CHI (83 g) were significantly greater than CHI (83 g) or CCI alone (p<0.05 for group).