Table 2.

Effect of administration of HS extract on rodent systolic and diastolic blood pressure.

Primary author, year	Condition	Sample size	Plant Part	Extract mode	Dose	End time point	Within group SBP	Between group SBP	Within group DBP	Between group DBP
Mojiminiyi, 2007	Normo	6 rats	C	W	1^a	1	Red		Red
Mojiminiyi, 2007	Normo	6 rats	C	W	5^a	1	Red		Red
Mojiminiyi, 2007	Normo	6 rats	C	W	25^a	1	Red		Red
Mojiminiyi, 2007	Normo	6 rats	C	W	125^a	1	Red		Red
Onyenekwe, 1999	Normo	5 rats	P	W	500^a	21	Red	N/A	Red	N/A
Onyenekwe, 1999	Normo	5 rats	P	W	1000^a	21	Red	N/A	Red	N/A
Mojiminiyi, 2007	Hyper^a	6 rats	C	W	1^a	1	NS		NS
Mojiminiyi, 2007	Hyper^b	6 rats	C	W	1^a	1	Red		Red
Mojiminiyi, 2007	Hyper^a	6 rats	C	W	5^a	1	Red		Red
Mojiminiyi, 2007	Hyper^b	6 rats	C	W	5^a	1	Red		Red
Mojiminiyi, 2007	Hyper^a	6 rats	C	W	25^a	1	Red		Red
Mojiminiyi, 2007	Hyper^b	6 rats	C	W	25^a	1	Red		Red
Mojiminiyi, 2007	Hyper^a	6 rats	C	W	125^a	1	Red		Red
Mojiminiyi, 2007	Hyper^b	6 rats	C	W	125^a	1	Red		Red
Odigie, 2003	Hyper	5 rats	P	W	250^a	56	Red	Dep	N/A	Dep
Onyenekwe, 1999	Hyper	5 mice	P	W	500^a	21	Red	Dep	Red	Dep
Onyenekwe, 1999	Hyper	5 mice	P	W	1000^a	21	N/A	N/A	N/A	N/A
Inuwa, 2012	Hyper	8 rats	C	W	10^b	70	Red	Dep	Red	Dep
Inuwa, 2012	Hyper	8 rats	C	W	15^b	70	Red	Dep	Red	Dep
Inuwa, 2012	Hyper	8 rats	C	W	20^b	70	Red	Dep	Red	Dep
Inuwa, 2012	Hyper	6 rats	F	A	50^a	5	NS		NS
Inuwa, 2012	Hyper	6 rats	F	A	100^a	5	NS		NS
Inuwa, 2012	Hyper	6 rats	F	A	200^a	5	NS		NS

Notes: Condition: Normo=normotension, Hyper=hypertension,

salt loaded induced,

chronic oxide synthase inhibition induced; Plant part used in extract=F=flower, C=calyx, P=petal L=leaf; Extract mode: W=water, A=alcohol;

Dose: ^a=mg of HS extract/kg weight of animal/day,

%; End time point: number of days after start of treatment when measurement was taken; SBP=Systolic blood pressure; DBP=Diastolic blood pressure; Results: N/A=not available, NS=not significant, Dep=depressed, Ele=elevated, Red=reduced, Inc=increased, depressed or elevated used accordingly when values compared with appropriate control, increased or reduced used when values compared between baseline and end of treatment within the same group