Table 5.
Cholesterol RCT interventions and effects of cholesterol RCT interventions on total cholesterol, HDL-C, LDL-C, and triglycerides.
| Primary author, year |
Condition | Sample size |
Substance | Plant part |
Extract mode |
Dose | # of doses per day |
Days dose taken |
TC (SD) |
p- value |
HDL- C (SD) |
p- value |
LDL- C (SD) |
p- value |
TG (SD) |
p- value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0 | 206 (39) | 44.3 (8.3) | 130.8 (29) | 153.5 (59) | ||||||||||||
| Mohagheghi, 2011 | Hyperten | 45(42) | HS | C | W | .015/2a | 2 | 15 | 212 (37) | Inc | 46 (7.2) | Inc | 133.2 (26) | NS | 157.5 (58) | NS |
| 0 | 202.6 (41.6) | 41.6 (10.3) | 124.1 (41.7) | 148.0 (61.3) | ||||||||||||
| Gurrola-Diaz, 2010 | None | 26 (26) | HS | C | A | 100b | 1 | 30 | 197.5 (37.0) | NS | 45.8 (9.3) | Inc | 124.5 (35.5) | NS | 113.8 (54.1) | Red |
| 0 | 199.8 (40.5) | 32.0 (5.8) | 130.1 (34.8) | 172.3 (107.4) | ||||||||||||
| Gurrola-Diaz, 2010 | MeSy | 18 (18) | HS | C | A | 100b | 1 | 30 | 179.7 (21.2) | Red | 44.5 (8.3) | Inc | 104.1 (20.4) | Red | 137.6 (62.1) | NS |
| 0 | 207.1 (32.5) | 42.0 (9.4) | 155.3 (13.9) | 159.9 (90.6) | ||||||||||||
| Kuriyan, 2010 | Hyperlip | 30 (28) | HS | L | A | 500b | 2 | 90 | 198.5 (33.2) | NS | 42.6 (8.9) | NS | 127.6 (24.1) | Red | 143.3 (73.9) | Red |
| 0 | 236.2 (58.1) | 48.2 (10.6) | 137.5 (53.4) | 246.1 (84.9) | ||||||||||||
| Mozaffari-Khosravi, 2009 | Diab | 30 (27) | HS | C | W | 2/240c | 2 | 30 | 218.6 (38.4) | Red | 56.1 (11.3) | Inc | 128.5 (41.2) | Red | 209.2 (57.2) | Red |
| Lin, 2007 | Hyperlip | 14 (N/A) | HS | F | W | 500b | 3 | 0 | 201.9 (27.2) | |||||||
| 28 | 194.6 (24.2) | Red | ||||||||||||||
| 6 | 0 | 223.4 (36.8) | ||||||||||||||
| Lin, 2007 | Hyperlip | 14 (N/A) | HS | F | W | 500b | 28 | 213.9 (37.0) | Red | |||||||
| 9 | 0 | 207.5 (26.5) | ||||||||||||||
| Lin, 2007 | Hyperlip | 14 (N/A) | HS | F | W | 500b | 28 | 212.6 (40.0) | NS |
Notes: Condition: Hyperten=hypertension, MeSy=metabolic syndrome, Hyperlip=hyperlipidemia, Diab=diabetes; Sample size= beginning of study (end of study), N/A=not available; Substance: HS=Hibiscus sabdariffa; Plant part used in extract=F=flower, C=calyx, L=leaf; Extract mode: W=water, A=alcohol;
Dose: a=g substance/glass of extraction substance,
b
mg of HS extract,
c
g of substance/mL of extraction substance; TC=total cholesterol, HDL-C= high-density lipoprotein cholesterol, LDL-C=low-density lipoprotein cholesterol, TG=triglycerides, SD=standard deviation; Results: NS=not significant, Reduced=Red, Increased=Inc