Table 1.
Ratio of phosphorylated to total protein levels after nicotine-DHβE treatment and 24 hr after spontaneous nicotine withdrawal. Ratios are expressed as a percentage of saline control.
Groups | pCaMKII:CaMKII | p603:synapsin I |
---|---|---|
Veh-veh precipitated | 99.96 ± 2.57 | 100 ± 12.24 |
Chronic nicotine | 128.74 ± 41.6 | 112.48 ± 27.6 |
Nic-DHβE precipitated | 95.86 ± 8.25 | 105.39 ± 12.62 |
Nic-MLA precipitated | 103.36 ± 15.67 | 90.5 ± 8.82 |
Saline spontaneous | 100 ± 7.78 | 100 ± 6.94 |
Nicotine spontaneous | 61.66 ± 10.9a | 72.11 ± 7.85a |
denotes P < 0.05 vs. corresponding spontaneous saline control. Veh, vehicle; nic, nicotine