Aldosterone deficiency does not prevent diet-induced obesity. Body weight increased significantly during HF feeding in both genotypes (a). Epididymal fat weight increased similarly in both genotypes (b). Fat mass and free fluid assessed by NMR increased in both genotypes during HF feeding (c, d), although muscle mass increased in wild-type mice but not in As−/− mice during HF feeding (c). White bar, wild-type; grey bar, As−/−; hatched bars, HF diet. *p<0.05, **p≤0.01, ***p≤0.001