Table 3.
Mean baseline volumes and 2-year changes in volume for the 35 cortical regions. Values are derived from the regional intercepts and slopes output by linear latent growth curve modeling. Mean absolute baseline volume and amount of 2-year change is in units of mm3. Standardized 2-year change is expressed in standard deviation units: a value of −1 indicates that on average, the region lost 1 standard deviation in volume over 2 years.
| Region | Mean Volume At Baseline | Mean Absolute 2-Year Change | Mean Standardized 2-Year Change |
|---|---|---|---|
| Hippocampus | 5808.8 | −302.4 | −0.29 |
| Banks of Superior Temporal Sulcus | 4195.8 | −187.9 | −0.24 |
| Caudal Anterior Cingulate | 3698.8 | −91.7 | −0.14 |
| Caudal Middle Frontal Gyrus | 10131.5 | −356.1 | −0.19 |
| Cuneus | 5013.4 | −37.4 | −0.04 |
| Entorhinal Cortex | 3397.7 | −219.7 | −0.27 |
| Frontal Pole | 1282.2 | −36.5 | −0.13 |
| Fusiform Gyrus | 16510.5 | −804.8 | −0.33 |
| Inferior Parietal Lobule | 21962.9 | −767 | −0.22 |
| Inferior Temporal Gyrus | 18768.4 | −993.4 | −0.31 |
| Insula | 11229.7 | −344.9 | −0.24 |
| Isthmus of Cingulate | 4012.3 | −154.6 | −0.24 |
| Lateral Occipital | 20562.1 | −453.3 | −0.14 |
| Orbital Frontal | 12527 | −353.1 | −0.24 |
| Lingual | 11320.8 | −203 | −0.12 |
| Medial Orbital Frontal | 7572.8 | −252.4 | −0.25 |
| Middle Temporal Gyrus | 18721.1 | −987.6 | −0.34 |
| Paracentral Lobule | 6258.9 | −95.5 | −0.09 |
| Parahippocampal Gyrus | 3746.4 | −190.9 | −0.33 |
| Pars Opercularis | 7269.4 | −232.8 | −0.19 |
| Pars Orbitalis | 4010.4 | −105.1 | −0.17 |
| Pars Triangularis | 5911.7 | −135.9 | −0.12 |
| Pericalcarine | 3486 | −19.4 | −0.03 |
| Postcentral gyrus | 15759.2 | −166.9 | −0.08 |
| Posterior Cingulate | 5833.4 | −196.8 | −0.24 |
| Precentral Gyrus | 21455.6 | −519 | −0.18 |
| Precuneus | 15309.1 | −511.3 | −0.23 |
| Rostral Anterior Cingulate | 3729 | −101.2 | −0.15 |
| Rostral Middle Frontal Gyrus | 24612.1 | −726.3 | −0.19 |
| Superior Frontal | 36011.3 | −1219.8 | −0.24 |
| Superior Parietal Lobule | 21432.3 | −477.4 | −0.15 |
| Superior Temporal Sulcus | 19043.8 | −747.8 | −0.27 |
| Supramarginal Gyrus | 17413.9 | −574.8 | −0.23 |
| Temporal Pole | 3806.8 | −234.2 | −0.37 |
| Transverse Temporal | 1703.1 | −66.1 | −0.2 |