Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Human Siglec5 is comprised of four extracellular domains, a transmembrane region and two intracellular inhibitory domains (A). The extracellular portion of the molecule is heavily glycosylated. (B) Intramolecular interactions are thought to be an important component of the immunomodulatory properties of siglec family proteins.
