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. Author manuscript; available in PMC: 2014 Jan 11.
Published in final edited form as: Neurotoxicol Teratol. 2013 Jan 11;35:34–45. doi: 10.1016/j.ntt.2013.01.001

Figure 4.

Figure 4

Locomotor activity with methamphetamine challenge—central distance (cm). Mice were re-acclimated to the test for 30 min prior to methamphetamine administration (1.0 mg/kg s.c.). After treatment with methamphetamine they were placed back in the test apparatus for an additional 180 min. Data are least square mean ± SEM per 5 min interval. *P<0.05, †P <0.10, CSE vs. Control. Note *P<0.05 with bracket indicates significant difference averaged across intervals for the pre-challenge test session. Post-challenge data were analyzed using the pre-challenge data as a covariate to control for differences in baseline prior to methamphetamine treatment. Group sizes: total (males/females): Control = 33 (15/18), CSE = 27 (14/13).