Table 2.
| Control | CSE | |||||
|---|---|---|---|---|---|---|
| Function | Test | Variable | M | F | M | F |
| Defensive Anxiety |
Number of Animals |
15 | 18 | 14 | 13 | |
| Marble Burying |
No. 2/3rd buried |
13.9 ± 0.4 | 14.1 ± 0.3 | 13.6 ± 0.4 | 13.8 ± 0.4 | |
| Startle | Number of Animals |
11 | 17 | 11 | 10 | |
| ASR | Peak Amplitude |
99.0 ± 12.0 | 128.0 ± 9.6 | 97.8 ± 12.0 | 143.0 ± 12.6 | |
| PPI | % Inhibition | PP70 | 42.5 ± 5.8 | 52.9 ± 4.7 | 48.2 ± 5.8 | 60.0 ± 6.1 |
| PP76 | 51.5 ± 5.8 | 61.7 ± 4.7 | 59.4 ± 5.8 | 70.9 ± 6.1 | ||
| PP80 | 51.8 ± 6.6 | 40.2 ± 6.5 | 40.5 ± 9.2 | 15.3 ± 9.2 | ||
| Working Memory |
Number of Animals |
15 | 18 | 13 | 13 | |
| MWM-MTS | T1-T2 (s) | −3.8 ± 3.3 | 3.0 ± 3.0 | 0.7 ± 3.6 | 6.6 ± 3.6 | |
| Emotional Learning |
Cond. Fear | Number of Animals |
M+F = 33a | M+F = 27a | ||
| % Freezing | Pre-tone | 0.4 ± 0.2 | 0.0 ± 0.2 | |||
| Post-tone | 52.0 ± 5.5 | 50.8 ± 6.1 | ||||
| Depression | Number of Animals |
15 | 18 | 14 | 13 | |
| FST | Immobility time (s) |
169.3 ± 15.0 | 169.1 ± 15.0 | 170.8 ± 15.5 | 153.3 ± 16.1 | |
| Spatial Learning |
Swim Speed | Number of Animals |
20 | 19 | 10 | 10 |
| Acquisition | cm/s | 17.4 ± 0.6 | 17.5 ± 0.6 | 16.2 ± 0.6 | 16.2 ± 0.7 | |
| Acq-probe | 18.4 ± 1.0 | 16.3 ± 1.0 | 15.4 ± 1.1 | 16.7 ± 1.1 | ||
| Reversal | 16.1 ± 0.8 | 16.6 ± 0.9 | 15.2 ± 0.9 | 15.7 ± 1.0 | ||
| Rev-probe | 14.5 ± 1.5 | 14.6 ± 1.7 | 11.8 ± 1.8 | 13.4 ± 1.8 | ||
| Shift | 14.2 ± 1.1 | 14.2 ± 1.1 | 12.4 ± 1.2 | 13.5 ± 1.2 | ||
| Shift-probe | 11.9 ± 1.7 | 11.3 ± 1.7 | 10.0 ± 1.9 | 10.7 ± 1.9 | ||
a
Imbalance in the number of males (M) versus females (F) on this test were such that one cell did not have sufficient numbers to be used statistically, therefore, for this test sexes were combined.