Skip to main content
. Author manuscript; available in PMC: 2014 Mar 15.
Published in final edited form as: J Immunol. 2013 Feb 6;190(6):2984–2993. doi: 10.4049/jimmunol.1201650

Figure 5. MIF-deficiency decreases lung metastasis in an experimental metastasis model of melanoma.

Figure 5

B16-F10-luc2 cells were injected into the tail vein of MIF+/+ and MIF−/− mice (n=10). (A) Ventral images taken on day 21 are shown for representative mice (n = 5). (B) Bioluminescence was quantified from the in vivo signals emitted from ventral views. Data shown are representative of three independent experiments (n = 5). (C) Mice were sacrificed on day 25 and lungs were perfused, harvested and photographed. (D) Lung tumor burden in tumor-bearing MIF+/+ and MIF−/− mice. Data represents the average weights of 4 sets of lungs/group ± SEM and are representative of two independent experiments. P value = *, p≤0.05.