Table 5. The Relationship Between Connectivity & Duration.
Region of interest (ROI) analysis of default mode network (DMN) connectivity v.s. duration of disease in epilepsy patients. VPA− = valproate non-responders, Seizures+ = uncontrolled seizures. Sample size (n), effect size, standard error (SE), degrees of freedom (DF), and two-sided p-values are shown.
| DMN v.s. Duration of Epilepsy | Effect Size | SE | DF | P-Value | |
|---|---|---|---|---|---|
| ICA & Dual Regression |
All Epilepsy (n=60) | −0.011 | 0.003 | 58 | 0.001 |
| Seizures− (n=44) | −0.007 | 0.004 | 42 | 0.086 | |
| Seizures+ (n=16) | −0.016 | 0.005 | 14 | 0.004 | |
| VPA+ (n=28) | 0.005 | 0.009 | 26 | 0.556 | |
| VPA− (n=13) | −0.019 | 0.003 | 11 | <0.001 | |
| Seed-Based Voxel Correlation |
All Epilepsy (n=60) | −0.002 | 0.020 | 58 | 0.939 |
| Seizures− (n=44) | 0.042 | 0.023 | 42 | 0.072 | |
| Seizures+ (n=16) | −0.066 | 0.030 | 14 | 0.042 | |
| VPA+ (n=28) | 0.115 | 0.040 | 26 | 0.008 | |
| VPA− (n=13) | −0.047 | 0.029 | 11 | 0.126 | |