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. Author manuscript; available in PMC: 2014 Mar 1.
Published in final edited form as: Rev Endocr Metab Disord. 2013 Mar;14(1):77–86. doi: 10.1007/s11154-012-9234-4

Fig. 4.

Fig. 4

Exercise kinetics correlate with slowed muscle O2 delivery: Muscle deoxyhemoglobin ([HHb]) concentration kinetics in a representative healthy subject and a subject with T2D at rest and following the onset of moderate exercise. Exercise begins at time = 0. Note pronounced overshoot of HHb in the T2D subject early in the exercise transition. This response indicates a greater reliance upon local muscle oxygen extraction (e.g. due to slowed increase in microvascular blood flow) early in exercise that is not observed in healthy muscle. Published in Bauer, TA et al. Diabetes Care. 2007 Nov;30(11):2880–5 [3]