Imaging of PEG/R8-LNPs and p54149-161-PEG/R8-LNPs for the analysis of intracellular trafficking. (a) PEG/R8-LNPs and (b) p54149-161- PEG/R8-LNPs encapsulating rhodamine-labeled pDNA were transfected to GFP/Tub-HeLa cells for 1, 2, and 3 hours (represented in left, middle, and right panels, respectively). GFP, green fluorescent protein; PEG, polyethylene glycol.