. Author manuscript; available in PMC: 2014 Feb 1.

Published in final edited form as: Curr Opin Chem Biol. 2013 Jan 1;17(1):20–26. doi: 10.1016/j.cbpa.2012.11.023

Table 1.

LYPLA1 and LYPLA2 inhibitors.

Inhibitor	LYPLA1 Inhibition	LYPLA2 Inhibition	References
Palmostatin B	IC₅₀ = 5.4 nM	IC₅₀ = 37.7 nM	[40,42–43]
Palmostatin M	IC₅₀ = 2.5 nM	IC₅₀ = 19.6 nM	[42–43]
LYPLA1 Inhibitor 21	K_i = 300 nM	K_i >10 µM	[47]
LYPLA2 Inhibitor 1	K_i >10 µM	K_i = 230 nM	[47]