. Author manuscript; available in PMC: 2013 Mar 11.

Published in final edited form as: Gynecol Oncol. 2008 May 21;110(2):196–201. doi: 10.1016/j.ygyno.2008.04.002

Table 2.

Area under the receiver operating characteristic (ROC-AUC) curves for individual and combined tumor marker assays for all Stages of endometrial cancer.

Marker Combination	ROC-AUC (95% CI) (Controls vs. All Endometrial Cancers Stages)

	All Stages	P-value for comparison of ROC-AUC to HE4
CA125	67.1% (61.3 - 72.9)	0.0007
HE4	78.7% (73.7 - 83.6)	---
CA72.4	55.0% (48.7 - 61.4)	<0.0001
SMRP	50.5% (44.3 - 56.8)	<0.0001
CA125 + HE4	79.4% (74.5 - 84.3)	0.4777
CA125 + CA72.4	66.5% (60.7 - 72.4)	0.0004
CA125 + SMRP	67.3% (61.6 - 73.1)	0.0010
HE4 + CA72.4	78.9% (73.9 - 83.8)	0.3066
HE4 + SMRP	78.8% (73.8 - 83.7)	0.3619
CA125 + HE4 + CA72.4	79.5% (74.6 - 84.4)	0.5289
CA125 + HE4 + SMRP	79.7% (74.8 - 84.5)	0.3654
CA125 + CA72.4 + SMRP	66.8% (61.0 - 72.6)	0.0005
HE4 + CA72.4 + SMRP	79.0% (74.0 - 83.9)	0.2993
CA125 + HE4 + CA72.4 + SMRP	79.7% (74.8 - 84.6)	0.4154