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. Author manuscript; available in PMC: 2013 Mar 11.
Published in final edited form as: Gynecol Oncol. 2008 May 21;110(2):196–201. doi: 10.1016/j.ygyno.2008.04.002

Table 5.

Sensitivities for individual and combined tumor marker assays in stage I endometrial cancer.

Marker Combination Controls vs. Endometrial Cancers – Stage I Average Sensitivity at Set Specificity of:
90% 95% 98%

CA125 30.0% 20.8% 12.9%
HE4 48.4% 37.9% 29.3%
CA72.4 7.6% 5.8% 3.8%
SMRP 14.4% 8.7% 4.4%
CA125 + HE4 51.6% 41.7% 34.4%
CA125 + CA72.4 29.9% 20.6% 13.6%
CA125 + SMRP 28.8% 20.5% 13.1%
HE4 + CA72.4 48.4% 37.9% 29.8%
HE4 + SMRP 48.3% 38.0% 29.2%
CA125 + HE4 + CA72.4 51.7% 40.7% 34.5%
CA125 + HE4 + SMRP 51.6% 41.7% 33.7%
CA125 + CA72.4 + SMRP 28.6% 20.1% 14.6%
HE4 + CA72.4 + SMRP 48.4% 37.9% 29.8%
CA125 + HE4 + CA72.4 + SMRP 51.7% 39.1% 34.6%