Table 1.

Neuronal uptake rates (K_up) and major clearance half-times (T_1/2) in isolated rat hearts^*.

Tracer	Acronym	Kup (ml/min/g wet)	Major Clearance T1/2 (h)	Ref.
[123I]-m-iodobenzylguanidine	[123I]MIBG	3.6 ± 0.2	3.5 ± 1.8	[24]
[11C]-(−)-m-hydroxyephedrine	[11C]HED	2.7 ± 0.4	1.1 ± 0.3	[25]
p-[18F]fluorobenzylguanidine	[18F]PFBG	1.2 ± 0.4	0.53 ± 0.06	[26]
[11C]4-fluoro-m-hydroxyphenethylguanidine	[11C]4F-MHPG	0.72	> 73	[12]
[18F]4-fluoro-m-hydroxyphenethylguanidine	[18F]4F-MHPG	0.68	> 13	This work

^*Extraneuronal uptake (uptake-2) was blocked pharmacologically.