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. Author manuscript; available in PMC: 2014 Mar 15.
Published in final edited form as: J Immunol. 2013 Feb 15;190(6):2913–2923. doi: 10.4049/jimmunol.1202670

Figure 4. The NF-κB inhibitors BAY-7085 and Parthenolide have differential effects on LPS-induced IκBα and IκBβ degradation in fetal PAEC.

Figure 4

A) Representative Western blot showing IκBβ and IκBα in whole cell lysates from fetal PAEC pretreated with BAY-7085 (0–10 µmol/L, 1h) prior to LPS exposure (10 ng/mL, 1h). Calnexin is shown as a loading control.

B) Representative Western blot showing IκBβ and IκBα protein in whole cell lysate from fetal PAEC pretreated with parthenolide (0–2 µmol/L, 1h), DMSO vehicle, or control, and prior to LPS exposure (10 ng/mL, 1h). Calnexin is shown as a loading control.