Dietary GSPs enhanced the production of IL-12 and IFNγ in DCs obtained from UVB-exposed wild-type mice but not DCs from XPA-KO mice. Mice were exposed to UVB three times on consecutive days. Mice were sacrificed 24 hours after the last UVB exposure, and DCs (CD11c+ cells) were isolated from the lymph nodes. DCs were stimulated with LPS (5μg/mL) for 48 hours, then harvested and supernatants collected. The concentrations of cytokines in the cell supernatants were estimated by ELISA and are presented as the mean ±SD in terms of pg/2 million cells. Experiment was repeated once; n=5. Significant decrease versus non-UVB control, ¶P<0.01; significant increase versus UVB alone, *P<0.01. Significant increase versus non-UVB control, †P<0.01, significant decrease versus UVB alone, **P<0.01.