Table 2. Pre-RRT nerve excitability results for HDF and HFHD groups compared to controls.
| Normal controls | HDF | HFHD | ANOVA F, p | |||
| Recovery Cycle | ||||||
| Refractoriness (%) | 19.3(±2.9) | 27.0(±7.2) | 60.4(±8.4)a,b | 15.4, <0.001 | ||
| Superexcitability (%) | −21.7(±1.5) | −12.2(±2.3)a | −2.0(±2.5)a,b | 29.0, <0.001 | ||
| Threshold Electrotonus | ||||||
| TEh (90–100 ms) (%) | −117(±3) | −112(±9) | −85(±8)a,b | 9.7, <0.001 | ||
| TEd (10–20 ms) (%) | 68.4(±1.0) | 59.6(±3.6)a | 53.1(±2.4)a | 17.7, <0.001 | ||
| TEd (90–100 ms) (%) | 45.4(±0.7) | 40.6(±2.2)a | 36.4(±1.6)a | 12.2, <0.001 | ||
| Current Threshold | ||||||
| Resting I/V slope | 0.60(±0.01) | 0.67(±0.07) | 0.84(±0.07)a,b | 8.3, 0.001 | ||
All values given as mean (±SEM). By convention threshold electrotonus, refractoriness and superexcitability are expressed as percentage change in threshold. TEd, depolarising threshold electrotonus; TEh, hyperpolarising threshold electrotonus; I/V, current threshold.
a
Significantly different to controls,
b
significantly different to HDF.