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. 2013 Mar 11;8(3):e59183. doi: 10.1371/journal.pone.0059183

Table 3. Comparative analyses of the IHC-based results on resection, biopsy and cytology specimens.

Judgment regarding positive result Type Sensitivity (%) Specificity (%) PPV (%) NPV (%) κ
Total 93.42 54.25 55.69 93.06 0.422
 = 0 as negative Resection 96.61 58.14 61.29 96.15 0502
≥1 as positive Biopsy 92.59 51.08 52.45 92.21 0.335
Cytology 83.33 59.09 52.63 86.67 0.181
Total 77.63 86.64 78.14 86.4 0.644
≤1 as negative Resection 79.66 93.02 88.68 86.96 0.739
≥2 as positive Biopsy 80.25 83.45 73.86 87.89 0.626
Cytology 50 81.82 60 75 0.331
Total 31.58 100 100 70.37 0.364
≤2 as negative Resection 30.51 100 100 67.72 0.342
 = 3 as positive Biopsy 34.57 100 100 72.4 0.4
Cytology 16.67 100 100 68.75 0.206