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. 2013 Mar 11;8(3):e58364. doi: 10.1371/journal.pone.0058364

Figure 4. Shift in the Balance between Pro- and Anti-Inflammatory Markers in Association with Plaque Regression.

Figure 4

A. Representative photomicrographs showing immunofluorescence staining of aortic sinus sections with CD68 (red) and its quantitative analysis (n = 10 per group). **P = 0.025 B. Representative photomicrographs showing immunofluorescence staining of aortic sinus sections with TNF-α (red) and its quantitative analysis (n = 6 per group). ***P = 0.001 C. Representative photomicrographs showing immunofluorescence staining of aortic sinus sections with TGF-β (red) and its quantitative analysis (n = 6 per group). ***P = 0.003 D. Paraffin-embedded aortic sinus sections stained with Masson’s trichrome (light blue) and quantitative analysis of collagen in lesion area (n = 6 per group). **P = 0.008. Scale bar represents 200 µm. Scale bar represents 50 µm for the immunofluorescence staining.