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. 2013 Mar 11;8(3):e58364. doi: 10.1371/journal.pone.0058364

Figure 6. Reduction in Plaque Vulnerability Markers in Tolerized Mice.

Figure 6

A. Representative photomicrographs showing immunofluorescence staining of aortic sinus sections with MMP9 (red) and its quantitative analysis (n = 10 per group). *P = 0.035 B. Representative photomicrographs showing immunofluorescence staining of aortic sinus sections with tissue factor (red) and its quantitative analysis (n = 6 per group). *P = 0.028 C. Representative photomicrographs showing immunofluorescence staining of aortic sinus sections with calprotectin (MRP8/14) (red) and its quantitative analysis (n = 6 per group). *P = 0.045 D. Representative photomicrographs of aortic sinus sections stained with alizarin-red S. (n = 6 per group) Arrows indicate calcium depositions and its quantitative analysis. *P = 0.018. Scale bar represents 150 µm. E. Representative photomicrographs of aortic sinus sections stained with Masson’s trichrome and its quantitative analysis (n = 8 per group). **P = 0.002. Lower photomicrograph shows picrosirius staining for collagen content Scale bar represents 200 µm. Scale bar represents 50 µm for the immunofluorescence staining.