Table 1.

DO-SBIS study protocol measures and outcome assessments

Timing	Assessment	N	Mode	Measures	Outcome
Pre-randomization	All United States Level I trauma center program coordinators	204	Phone	Alcohol SBI Readiness Survey	Classification/selection of RCT middle majority adopter sites
Pre-randomization	Middle majority adopter trauma centers	40	Phone	Early adopter status interview assessment	Selection of site trauma surgeon and SBI provider interventionist(s)
Pre-randomization baseline, 1-week, 1-, 4-, 7-, 17-, and 27-month follow- up	Alcohol SBI champion(s)	20+	Phone	MITI-coded standardized patient actor interviews [34]	Motivational interviewing intervention fidelity and skill level
Pre-randomization baseline, 7-, 17-, and 27-month follow-up	Trauma center staff comprising alcohol SBI work unit	10*20	Web	Organizational Social Context and Readiness [44, 45]	Organizational climate, culture, and readiness for change
Pre-intervention, 6-, and 12-month post-hospital admission	Patient self-report of primary alcohol outcomes	800	In-person/ Phone	AUDIT, Form 90, and SIP [33, 34]	Alcohol consumption and alcohol use problems
Pre-intervention, 6-, and 12-month post-hospital admission	Patient self-report of secondary outcomes including PTSD, depression, drug use & function	800	In-person/ Phone	Multiple (PCL-C, PHQ- 9, Form 90 drug, MOS SF-12) [41-43]	Trauma center secondary outcomes
RCT recruitment period	Patient trauma registry data	800	CONSORT	Diagram of patient flow through protocol at 20 sites	Estimation of target population and intervention reach
RCT development and implementation	Study intervention team members’ records	5	Computer entry	Logs and field notes	Intervention activity documentation
Study end-point	Trauma center SBI champion(s)	20	In-person/ Phone	Semi-structured qualitative interviews	Facilitators and barriers to SBI implementation and maintenance