Robust rescue of v-Src toxicity is dependent on PTP activity. Yeast strains expressing v-Src alone (○), v-Src and a wild-type PTP domain (●; A: PTP1B, B: TCPTP, C: Shp2, D: PEST, E: PTPα), or v-Src and the corresponding phosphatase-dead mutant (▼; A: C215S PTP1B, B: C216S TCPTP, C: C459S Shp2, D: C231S PEST, E: C433S PTPα) were grown in a 96-well plate at 30 °C. OD600 readings for the cultures were measured every five hours