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. Author manuscript; available in PMC: 2014 Mar 15.
Published in final edited form as: J Immunol. 2013 Feb 1;190(6):2659–2669. doi: 10.4049/jimmunol.1202531

Figure 7. The expanded population of γδ NKT cells in the thymus of Itk−/− mice include cells derived from both fetal and adult progenitors.

Figure 7

The graph shows the relative proportions of in-frame TCR Vδ6 and Jδ1 junctions in three subsets of sorted thymocytes from WT-4Get and Itk−/−-4Get mice that derive from fetal versus adult progenitors. Populations analyzed were: CD122−GFP+ (Stage 1), CD122+GFP+ (Stage 2), and CD122+GFP− (Stage 3). The total number of sequences included in the analysis is indicated above each bar. Statistically significant differences were determined using the exact binomial test of goodness-of-fit, and p values are shown. At the right, the gating strategy for isolation of each thymocyte subset is shown.