Leg measurements of WT, MPS I, and VII mice. Measurements of the length of the tibia and foot from the posterior calcaneus to the distal end of the distal phalanges, and the diameter of the mid-femur of mice over 12 weeks of age. Error bars are +/− 1 SD. P-values less than 0.05 in comparison with WT mice are represented by an asterisk. WT mice, n=5. MPS I, n=3. MPS VII, n=4.